After installing the Honest Hearts DLC for Fallout New Vegas, all of the sudden the in-game sound stops working the second I load a savegame. Running FalloutNV.exe from the console, I get tons of these as soon as the game goes mute:
fixme:quartz:Parser_QueryInterface No interface for {2dd74950-a890-11d1-abe8-00a0c905f375}!
fixme:quartz:Parser_QueryInterface No interface for {2dd74950-a890-11d1-abe8-00a0c905f375}!
fixme:quartz:Parser_QueryInterface No interface for {2dd74950-a890-11d1-abe8-00a0c905f375}!
fixme:quartz:Parser_OutputPin_QueryInterface No interface for {56a868a5-0ad4-11ce-b03a-0020af0ba770}!
fixme:quartz:Parser_OutputPin_QueryInterface No interface for {56a868a5-0ad4-11ce-b03a-0020af0ba770}!
fixme:quartz:Parser_QueryInterface No interface for {2dd74950-a890-11d1-abe8-00a0c905f375}!
fixme:quartz:Parser_QueryInterface No interface for {2dd74950-a890-11d1-abe8-00a0c905f375}!
As a quick workaround, go into your Wine configuration, create a custom application setting for Fallout if you haven’t already, click the Libraries tab and add an override for quartz.
Native then Builtin did the trick for me.